English Views: 67 Author: Site Editor Publish Time: 2023-01-09 Origin: Site
Common aerosol filling machines include automatic aerosol filling machines, high-speed aerosol filling machines, and semi-automatic aerosol filling machines. With the continuous rise of domestic labor costs, with the development of automatic filling machines, automation and intelligence will receive more and more attention.
What is the necessity for the aerosol filling machine to appear?
What is the importance of aerosol filling machine?
How to use aerosol filling machine?
(1) The container produced by the aerosol filling machine can be used to store the medicine, and can be directly applied to the action site or absorption site, with a very obvious quick-acting effect and positioning effect, especially in respiratory tract administration. It has the advantages that other dosage forms cannot replace.
(2) The drug is packaged in the airtight container produced by the aerosol filling machine, which can maintain a clean and sterile state, reducing the chance of drug contamination, and the residual drug after stopping is not easy to cause environmental pollution. In addition, because the container is opaque, shielded from light, and not in direct contact with oxygen and moisture in the air, it is beneficial to improve the stability of the drug.
(3) It is easy to use, just press (suck), and it is suitable for all ages. It helps to improve the patient's medication compliance, especially for OTC drugs.
(4) Systemic medication can reduce the irritation of the drug to the gastrointestinal tract and avoid the first-pass effect of the liver.
(5) Medicinal aerosols are equipped with quantitative valves, so the dosage is accurate.
The difference between aerosols and most other dosage forms is that the packaging of such preparations requires pressure-resistant containers, valve systems and special aerosol filling machines, so the product cost is higher. In addition, propellants (mainly chlorofluoroalkanes), which are an important part of aerosols, can destroy the ozone layer, which has serious environmental protection problems, and can sensitize the heart and cause arrhythmia when reaching a certain concentration in animals or humans. . The "Montreal Treaty" signed by more than 140 countries requires a complete ban on the use of chlorofluoroalkane propellants in 2005. Therefore, the development of non-chlorofluoroalkane propellants with excellent performance faces severe challenges.
First, pour the prepared liquid medicine (usually the ethanol solution or aqueous solution of the drug) into the container at room temperature, then install the valve and squeeze it tightly, and then press the quantitative propellant through the aerosol filling machine (preferably air from the container). The liquefied propellant enters the aerosol filling machine after being filtered by a sand bar. The operating pressure is preferably 68.65 ~ 105.975kPa. When the pressure is lower than 41.19kPa, filling cannot be performed. When the pressure is low, the propellant cylinder can be heated with hot water or infrared rays to reach the working pressure. When the container is topped up, the filling needle extends into the valve stem, the aerosol filling machine and the valve of the container are opened at the same time, and the liquefied propellant expands and presses into the container.
For more information about aerosol filling machine, please contact Yangzhou Meida Filling Machinery Co.,Ltd has committed to providing the increasing of aerosol filling machine, and make them more effective, reliable, and consistent.
